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Boothman1* 1Simmons Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX 75399; 2Department of Basic Pharmaceutical Sciences & Mary Bapp Randolph, West Virginia University, Morgantown, WV 26506 * Address all correspondence to: David A.

PEG is completely water 1029 0724-8741/07/0600-1029/0 # 2007 Springer Science + Business Media, LLC Pharmaceutical Research, Vol. 24, No. 6, June 2007 (#2007 ) DOI: 10.1007/s11095-006-9223-y 1 Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center at Dallas, 5323 Harry

In preparation for AAS analysis, the livers were divided into three segments around the center (implantation site) and three 2-mm thick slices were sectioned from each segment.

The result is the forma- *Present address: Simmons Comprehensive Cancer Cen- ter, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390-8590 Correspondence to: J.

, placental formation, and cancer metastasis (Aguilar et al., 2013; Chen and Olson, 2005; Gast et al., 2018; Hernández and 1Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. 2Department of Molecular Biology, UT Southwestern Medical Center

Universitya; Departments of Surgery (Dr Abbott) and Anesthesiology (Dr Jones), Massachusetts General Hospitalb; Department of Biomedical Engineering, Case Western Reserve Universityc; School of Medicine and Biomedical Sciences, State University of New York at Buffalod; Children’s Nutrition Research Center

Chenb,c, Jinming Gaoa,⁎ a Department of Pharmacology, Simmons Comprehensive Cancer Center, 5323 Harry Hines Blvd., Dallas, TX 75390, USA b Department of Molecular Biology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX 75390, USA c Howard Hughes Medical Institute

The SASA is deter- mined from the area of the surface traced by the center of a probe sphere (e.g., 1.4 A for water) as it is rolled over the van der Waals surface of a molecule.

NICK FELIX VAJDOS,' LANETTE FEE,' GERALD GRIMSLEY,' AND THERONICA GRAY' ' Department of Medical Biochemistry and Genetics, 'Department of Biochemistry and Biophysics, and Center for Macromolecular Design, Texas A&M University, College Station, Texas 77843-1 I14 (RECEIVED Jbiy 12,